Computer-supported collaborative cearning (CSCL) is a recent approach to creating powerful learning and communication environments in combination with collaborative learning ideas and networked technology. Many advanced technical infrastructures for fostering higher-level processes of inquiry-based interaction have been developed (Edelson, Gordin, & Pea, 1999; Scardamalia & Bereiter, 1996). This chapter discusses instructional support in CSCL. First, the basic processes of instructional scaffolding in the context of CSCL are discussed, then relevant instructional models dealing with collaborative learning are presented. The specific focus is to introduce ‘basic models’ from the cooperative learning tradition to the more recent inquiry models, which are applicable to CSCL. The relationship between instructional support and issues of human learning and the educational setting is also discussed and cases of instructional support in CSCL are presented.