Collaborative learning involves synergistic efforts of students working together to reach a shared academic goal. Collaborative learning in the online environment (CoL) can contribute to meaningful, active learning and yield positive benefits to student achievement; however, designing and implementing CoL activities is challenging relating to distance barriers and varying student learning and communication preferences. The Universal Design for Learning (UDL) framework addresses these challenges as part of curricular design by incorporating flexibility into the way CoL activities are structured and providing options for learners in how they engage with the activities and express themselves. A conceptual model is proposed that situates CoL within the UDL framework and illustrates how CoL is facilitated by supportive technologies. Examples in the areas of online discussions and peer teaching are explored.