This chapter describes how to design a Methods of Teaching Computer Science (MTCS) course within an academic computer science teacher preparation program, and suggests two possible syllabi for such a course. It is emphasized, however, that different approaches and frameworks can be applied when one designs the course. In the first section of this chapter, we propose four possible perspectives on the MTCS course: the NCATE standards, merging computer science with pedagogy, Shulman´s model of teachers´ knowledge, and research findings. The second section of the chapter describes two MTCS course syllabi. We mention that though the focus in this section is placed on the MTCS course, the course models, as well as parts of them, can be used also for other purposes related to computer science teaching, such as curriculum design and professional development of computer science teachers.